Best of E3 2010 Awards - Best Wii Game

入選：
● Disney發行的Disney Epic Mickey
● Nintendo發行的Donkey Kong Country Returns
● Nintendo發行的Kirby's Epic Yarn
● Nintendo發行的The Legend of Zelda: Skyward Sword
● Nintendo發行的Metroid: Other M
獲獎：
Nintendo發行的Metroid: Other M